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Five Topmost Addictive Substances in the World The nicotine in tobacco is a highly addictive substance that makes people dependent on the product. This is dangerous because tobacco use is a major risk factor for many cardiovascular and respiratory Smoking is addictive Back of pack Cigarette is a highly addictive drug 19 Most Addictive Substances and Their Risks Avenues Recovery Tobacco : Behind the Smoke (infographic)
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